Journal Feed Weekly Wrap-Up

We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter. 

Originally published at JournalFeed, a site that provides daily or weekly literature updates. 

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#1: Battle of the Catecholamines – Epi vs Norepi for Post-Resuscitation Shock

Spoon Feed
Continuous epinephrine infusion for post-resuscitation shock in out of hospital cardiac arrest (OHCA) was associated with both higher all-cause and cardiovascular specific mortality when compared to norepinephrine.

Source
Epinephrine versus norepinephrine in cardiac arrest patients with post-resuscitation shock. Intensive Care Med. 2022 Mar;48(3):300-310. doi: 10.1007/s00134-021-06608-7. Epub 2022 Feb 7.


#2: CHOICE RCT – Post-Thrombectomy tPA for Stroke

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Among patients with acute ischemic stroke with large vessel occlusion that have been successfully reperfused with thrombectomy, the use of post-thrombectomy adjunctive intra-arterial alteplase results in greater likelihood of excellent neurologic outcome at 90 days – modified-Rankin score 0 or 1 – when compared with placebo.

Source
Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial. JAMA. 2022 Feb 10;e221645. doi: 10.1001/jama.2022.1645. Online ahead of print.

Spoon Feed
This literature review helps emergency physicians systematically approach evaluation of traumatic arthrotomy (TA) while pointing out diagnostic pitfalls.

Source
High risk and low prevalence diseases: Traumatic arthrotomy. Am J Emerg Med. 2022 Jan 21;54:41-45. doi: 10.1016/j.ajem.2022.01.013. Online ahead of print.

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