In the Literature

Controversies in Pulmonary Embolism Imaging and Treatment of Subsegmental Thromboembolic Disease

Pulmonary embolism (PE) is classically a life-threatening diagnosis, often considered in the work-up of patients with chest pain or dyspnea. Initial mortality rates of missed, untreated PE has been quoted as high as 26%, based on a 1960 study. This disease is common, with 400,000 patients affected with nonfatal PE and another 200,000 patients in the U.S. dying each year from this disease. PE is the third most common cause of death in cardiovascular disease after myocardial infarction and stroke.

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Penetrating Trauma: What We Miss and How We Can Improve

The patient with penetrating trauma can present with many different injuries. The majority of injuries are easily diagnosed. What about the patient with pneumothorax, diaphragmatic injury, ureteral injury, and hollow viscus injury? These are not so easy to diagnose, and delay in management can cause significant morbidity and mortality. This post provides pearls and pitfalls for these conditions.

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ED CRASH Course: TXA MATTERS!

Your shift starts and all of your patients are bleeding! There is an MVC victim with a tense abdomen and traumatic brain injury, a patient with an upper GI bleed, a woman whose spontaneous vaginal delivery has turned into a post-partum hemorrhage, and a brisk epistaxis in the back hallway. You thank the triage nurse and begin resuscitative measures. What role does tranexamic acid (TXA) play in the treatment of these patients?

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