#1: Cirrhotic UGIB – Do Antibiotics Actually Help?
Spoon Feed —
In cirrhotic upper GI bleeding (UGIB) patients, guidelines recommending routine 5–7 days of prophylactic antibiotics did not lower mortality compared with shorter courses, or no antibiotics, in a contemporary Bayesian meta-analysis.
Source
Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis: A Systematic Review and Bayesian Meta-Analysis. JAMA Intern Med. 2025 Aug 11:e253832. doi: 10.1001/jamainternmed.2025.3832. Epub ahead of print. PMID: 40788637; PMCID: PMC12340683
#2: Ondansetron to Go? It Works!
Spoon Feed —
Giving kids ondansetron to take home after an ED visit for vomiting due to gastroenteritis significantly reduced the risk of developing moderate-to-severe disease.
#3: STANDING Algorithm for Vertigo – How Accurate Is It?
Spoon Feed —
In ED patients with vertigo, the STANDING algorithm had high diagnostic accuracy and negative predictive value for central causes while reducing CT imaging and length of stay compared to “usual care.” But the main caveat here was that these emergency physicians underwent dedicated training in the algorithm.