Journal Feed
We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter.
Originally published at JournalFeed, a site that provides daily or weekly literature updates.
Follow Dr. Clay Smith at @spoonfedEM, and sign up for email updates here.

#1:  NIPPV and Lower Mortality in Severe Asthma

Spoon Feed
This retrospective, propensity-matched study of adult and pediatric patients with severe asthma confirms what we already know clinically: non-invasive positive pressure ventilation (NIPPV) decreases mortality and need for intubation.

Source
Association Between Noninvasive Positive Pressure Ventilation Use and Clinical Outcomes During a Severe Asthma Exacerbation: A Cohort Study. Crit Care Med. 2026 Jan 14. doi: 10.1097/CCM.0000000000007025. Epub ahead of print. PMID: 41532815.


#2: Is CT Accurate for Globe Rupture?

Spoon Feed —
When eye exam is limited by trauma, we rely on orbital CT. While specificity is 94%, sensitivity is only 75% for open globe injuries (OGI), making surgical consultation necessary when suspicion remains.

Source
Diagnostic test accuracy of CT for open globe injury: A systematic review and meta-analysis of overall impression and individual imaging signs. Injury. 2026 Jan 10;57(3):113041. doi: 10.1016/j.injury.2026.113041. Epub ahead of print. PMID: 41534455.


#3: Non-IV (PO or IN) Ketamine for Pediatric Sedation?

Spoon Feed —
This systematic review suggests that non-injectable ketamine (oral or intranasal) can provide effective and safe pediatric procedural sedation, particularly compared with other oral agents, although the certainty of evidence is low.

Source
Non-Injectable Ketamine for Pediatric Sedation in the Emergency Department: A Systematic Review.Acad Emerg Med. 2025 Dec;32(12):1344-1355. doi: 10.1111/acem.70163. Epub 2025 Oct 10. PMID: 41069251.

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