Journal Feed Weekly Wrap-Up

We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter. 

Originally published at JournalFeed, a site that provides daily or weekly literature updates. 

Follow Dr. Clay Smith at @spoonfedEM, and sign up for email updates here.


#1: No More LPs? Can CT Rule Out SAH 24-48 Hours From Onset?

Spoon Feed
Non-contrasted multislice CT (MSCT) is known to be highly sensitive in detecting subarachnoid hemorrhage (SAH) when performed within 6 hours of headache onset. Now, with modern MSCT, it looks like we can safely extend the timeframe even more.

Source
Sensitivity of modern multislice CT for subarachnoid haemorrhage at incremental timepoints after headache onset: a 10-year analysis. Emerg Med J. 2022 Nov;39(11):810-817. doi: 10.1136/emermed-2020-211068. Epub 2021 Nov 24.


#2: Does Calcium Work for PEA in Suspected Hyperkalemia?

Spoon Feed
Empiric calcium administration in PEA arrest not only failed to improve ROSC, but also had no impact when ECG features of hyperkalemia and acute myocardial ischemia were present.

Source
Effect of Calcium in Patients with Pulseless Electrical Activity and Electrocardiographic Characteristics Potentially Associated with Hyperkalemia and Ischemia-Sub-study of the Calcium for Out-of-hospital Cardiac Arrest (COCA) trial. Resuscitation. 2022 Nov 17;S0300-9572(22)00712-2. doi: 10.1016/j.resuscitation.2022.11.006. Online ahead of print.

Spoon Feed
Targeting a lower oxygen saturation (90-94%), compared to standard care (98-100%), in patients who were resuscitated after out-of-hospital cardiac arrest (OHCA) until admission to the intensive care unit did not significantly improve survival to hospital discharge.

Source
Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial. JAMA. 2022 Nov 8;328(18):1818-1826. doi: 10.1001/jama.2022.17701.


#4: PILOT RCT – Do Oxygen Targets Matter in Critically Ill Patients?

Spoon Feed
Among adult patients receiving mechanical ventilation, there was no significant difference in ventilator-free days or 28-day mortality between groups in which a lower (88-92%), intermediate (92-96%), or higher SpO2 target (96-100%) was used.

Source
Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation. N Engl J Med. 2022 Nov 10;387(19):1759-1769. doi: 10.1056/NEJMoa2208415. Epub 2022 Oct 24.

Leave a Reply

Your email address will not be published. Required fields are marked *