#1: Does Stress Ulcer Prophylaxis with a PPI Work?
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An international, multi-center RCT found that administering pantoprazole to intubated ICU patients lowered the rate of upper GI bleeding compared to placebo.
Source
Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation. N Engl J Med. Published online June 14, 2024. doi:10.1056/NEJMoa2404245
#2: GRACE-4 – New Guidelines for Alcohol Withdrawal, Alcohol Use Disorder, and Cannabis Hyperemesis
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GRACE-4 is packed with practice-changing recommendations for patients with alcohol withdrawal syndrome (AWS), alcohol use disorder (AUD), and cannabinoid hyperemesis syndrome (CHS).
Source
Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department. Acad Emerg Med. 2024 May;31(5):425-455. doi: 10.1111/acem.14911. PMID: 38747203.
