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Journal Feed Weekly Wrap-Up

We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter.
Originally published at JournalFeed, a site that provides daily or weekly literature updates.
Follow Dr. Clay Smith at @spoonfedEM, and sign up for email updates here.

#1: Break the Enchantment – Intensive BP Control and Brain Swelling

Spoon Feed —
Intensive blood pressure lowering after thrombolysis in acute ischemic stroke did not significantly reduce brain swelling compared to standard BP management.

Source
Effects of Intensive Blood Pressure Lowering on Brain Swelling in Thrombolyzed Acute Ischemic Stroke: The ENCHANTED Results. Stroke. 2025 Jun;56(6):1388-1395. doi: 10.1161/STROKEAHA.124.049938. Epub 2025 Apr 3. PMID: 40177745

#2: Liberal vs. Conservative Fluid in Sepsis + CHF

Spoon Feed —
This systematic review and meta-analysis found no significant difference in outcomes between conservative and liberal IV fluid resuscitation strategies in septic patients with CHF, CKD, or cirrhosis, highlighting the need for high-quality randomized trials in these high-risk populations.

Source
Conservative versus liberal fluid resuscitation for septic patients at risk for fluid overload: A systematic review with meta-analysis. J Crit Care. 2025 Jun;87:155045. doi: 10.1016/j.jcrc.2025.155045. Epub 2025 Feb 28. PMID: 40023080

#3: How Fast to Rewarm Hypothermic Patients?

Spoon Feed —
A faster early rewarming rate of 3º per hour, when going from very cold to 33ºC, was associated with improved 28-day survival and favorable neurological outcome.

Source
Association Between Rewarming Rate and Survival and Neurologic Outcome of Accidental Hypothermia. Crit Care Med. 2025 Jul 1;53(7):e1416-e1425. doi: 10.1097/CCM.0000000000006712. Epub 2025 Jun 3. PMID: 40459372.

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