52 in 52 – #29: The “PAMPer” Study
52 in 52 looks at the PAMPer study this week.
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transfusion
52 in 52 – #27: Immediate Transfusion in African Children with Uncomplicated Severe Anemia
This week the 52 in 52 series covers an RCT from the New England Journal of Medicine: Immediate Transfusion in African Children with Uncomplicated Severe Anemia.
EM@3AM: Transfusion Associated Circulatory Overload
A 67-year-old female with a history of CHF and CKD was brought in by ambulance from her nursing home for a gastrointestinal bleed. The patient’s total fluid balance from her nursing home was 2.5L over the past 24 hours. Her point of care hemoglobin is 4 g/dL and a transfusion of 2U pRBC and 1 FFP was initiated, though within approximately 1 hour of starting the transfusion, the patient became acutely short of breath and stated she was having severe difficulty breathing. What’s the next step in your evaluation and treatment?
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Whole Blood in Trauma: Ready for Primetime?
Is whole blood ready for routine use in trauma? What is the evidence behind it? This post evaluates whole blood and provides a glimpse into a currently-used protocol.
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Severe Transfusion Reactions and their ED-focused management
Transfusions can be life-saving, with the need for transfusion based on the indication, the patient, and the situation. Transfusion reactions, though rare, can be deadly. What do you need to know about these reactions? Read on to find out.
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RBC Transfusion in the Emergency Department
Struggling to decide if your patient requires a RBC transfusion? Read on: we’ll review the most recent studies and evidence-based guidelines to aid in your clinical decision-making.
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Massive Blood Transfusion
“There has been ongoing controversy regarding the ratio of components that should be given during massive transfusion”
How do you avoid inducing a coagulopathy in trauma patients requiring massive blood transfusion? Zach Radwine, MD summarizes the recent evidence for the 1:1:1 ratio.
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Bleeding in the Patient with Renal Failure
“Within the next decade, the incidence of CKD is expected to nearly double”
In this article, Matt Smetana, DO describes the common manifestations of hemorrhage in uremic patients, and then outlines strategies to stop the bleeding.
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