#1: Fewer Admissions? Just Add Ipratropium
Spoon Feed —
This systematic review found that nebulized ipratropium bromide (IB), in addition to standard first-line asthma treatment, decreased pediatric hospitalization rates, with no increase in adverse events. Significantly improved asthma clinical scores were seen with administration of nebulized or inhaled IB.
Source
Use of inhaled/nebulised ipratropium bromide in addition to standard first-line treatment with inhaled/nebulised short-acting beta 2-agonist and systemic steroid in the management of acute asthma exacerbations: a systematic review and meta-analysis of randomised controlled trials. Arch Dis Child. 2026 Feb 19;111(3):211-218. doi: 10.1136/archdischild-2024-327898. PMID: 41224524.
#2: Prolonged Prehospital Pediatric CPR Survival—Not Good
Spoon Feed —
In pediatric out-of-hospital cardiac arrest, the probability of survival drops below 1% after ~15 minutes of EMS CPR without ROSC, providing objective data to inform management and termination decisions.
Source
Duration of emergency medical services-initiated prehospital cardiopulmonary resuscitation efforts and survival for pediatric patients with out-of-hospital cardiac arrest. Resuscitation. 2026 Feb 25:111028. doi: 10.1016/j.resuscitation.2026.111028. Epub ahead of print. PMID: 41759813.
