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Journal Feed Wrap-Up

Journal Feed
We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter.
Originally published at JournalFeed, a site that provides daily or weekly literature updates.
Follow Dr. Clay Smith at @spoonfedEM, and sign up for email updates here.

#1: TOWAR RCT—Whole Blood vs Components Prehospital

Spoon Feed —
Compared to blood component therapy, no mortality benefit resulted from prehospital transfusion of low-titer group O whole blood (LTOWB) for adult trauma patients with hemorrhagic shock transported by helicopter EMS (HEMS).

Source
Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage. N Engl J Med. 2026 May 18. doi: 10.1056/NEJMoa2602167. Epub ahead of print. PMID: 42150044.

#2: Crying Babies, Hidden Causes? Unmasking Why They Cry

Spoon Feed — 
Among infants referred for excessive crying, approximately 1 in 10 were ultimately diagnosed with an underlying organic condition, with cow’s milk allergy accounting for the vast majority of cases.

Source
Prevalence of underlying organic causes in infants presenting with excessive crying: a 2-year follow-up study. Eur J Pediatr. 2026 Jun 11;185(7):485. doi: 10.1007/s00431-026-07155-3. PMID: 42274798.

#3: Bicarb for In-Hospital Cardiac Arrest—Better pH, Same Mortality

Spoon Feed —
In this randomized trial of patients with in-hospital cardiac arrest, administration of sodium bicarbonate did not result in a difference in sustained ROSC, mortality, or favorable neurologic outcome.

Source
Bicarbonate for In-Hospital Cardiac Arrest (BIHCA) Investigators. Sodium Bicarbonate for In-Hospital Cardiac Arrest: A Randomized Clinical Trial. JAMA. 2026 Jun 11:e2610628. doi: 10.1001/jama.2026.10628. Epub ahead of print. PMID: 42273960; PMCID: PMC13261510.

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