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A 45-year old African American woman presents with progressive fatigue over the past week and has experienced intermittent episodes of severe hand pain that typically self-resolve. She has also noted a worsening headache over the last day. Her blood pressure is 197/105 mm Hg and heart rate is 90 bpm. The physical exam is notable for smooth and taut skin on the patient’s face and hands. Laboratory values show a creatinine of 3.1 mg/dL. What is the likely diagnosis?

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Anticoagulation with heparin in PE

If patient needs heparin, consider using LMWH instead of UFH

 

LMWH more effective in PE, less bleeding, uses subcutaneous route

 

UFH may be preferred for cardiac arrest or persistent shock, ESRD, invasive procedure or surgery required, or active major bleeding

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